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Chondral and osteochondral injuries Injury Damage to chondral matrix andor cells andor subchondral bone without visible disruption of the articular surface Cartilage disruption (chondral fractures or ruptures) Cartilage and bone disruption (osteochondral fractures) Clinical presentation No known symptoms, although subchondral- bone injury may cause pain Inspection of the articular surface and current clinical imaging methods for articular cartilage cannot detect this type of injury Imaging of subchondral bone may show abnormalities May cause mechanical symptoms, synovitis, pain, and joint effusions May cause mechanical symptoms, synovitis, pain, and joint effusions Repair response Synthesis of new matrix macromolecules Cell proliferation.

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